The Zosimaia School of Ioannina (in Epirus) has been one of the most significant Greek middle-level educational institutions. The Zosimaia was founded at 1828 through the personal expense of the Zosimas brothers, and is still functioning as a high school under the regulations of the Greek Ministry of Education.

The Zosimaia functions continuously to the present day as a high school offering high level education, under the regulations of the Greek ministry of education.