The Archaeological Museum of Thessaloniki is a museum in Thessaloniki, Central Macedonia, Greece. It holds and interprets artifacts from the Prehistoric, Archaic, Classical, Hellenistic and Roman periods, mostly from the city of Thessaloniki but also from the region of Macedonia in general.

Notable exhibits

• Derveni krater
• The statue of Harpocrates (2nd century AD)
• The Head of Serapis (2nd century BC)
• Bronze helmet and gold mask (cemetery of Sindos, end of 6th century BC)
• Marble door (Macedonia tomb of Agia Paraskevi)
• Copy of “Unveiling” Aphrodite (421/420 BC)
• Gold medals (250–225 BC)
• Inlaid floors (mosaic)
• Gold diadems, gold disks and gold Medusa heads (350-325 BC)
• Derveni Papyrus (end of 5th century BC)