The Hogeschool provides exclusively art-related university-level higher education, hence the name. It houses around 1,000 students across its academic provision, and can trace its roots back to the first foundation of a Sint-Lukas art school in 1880. The school offers master programmes (four years) across the disciplines of audio-visual arts, graphic and publicity design, photography and fine art and bachelor programmes in interior design and construction. It also organizes Transmedia, a postgraduate programme for art students.

The Hogeschool actively encourages student mobility, and maintains several links with art schools across the continent through the Socrates programme and the Erasmus programme, with language of instruction to exchange students being English in the appropriate circumstances.